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These data confirmed that OA-NPs@OA could specifically target CD44-aberrant keratinocytes in vivo, enhancing the cellular uptake (Fig

In addition, liraglutide is able in vitro to shift the polarized macrophage phenotype from the pro-inflammatory M1 phenotype to the M2 anti-inflammatory phenotype

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The cAMP signaling pathway potentially enhances melanin production and deposition, which serves as a natural defense against UV penetration and facilitates nucleotide excision repair (NER), a crucial process for potentially removing UV-induced DNA lesions and averting mutagenesis