long-term effects of semaglutide Semaglutide: Double-edged Sword with Risks and Benefits Semaglutide (Ozempic) Injection: Uses, Benefits,

According to a 2022 review, gastrointestinal side effects, including constipation, were among the most commonly reported adverse effects of GLP-1 receptor agonists, especially during the dose-escalation phase in about 25-35% of users

doi: 10.1016/j.phymed.2019.153107 76

Schedule: Daily subcutaneous injections for 812 weeks (extend to 16 weeks if research goals require)

Pregnancy and Contraception GLP-1 receptor agonists are not recommended during pregnancy due to potential risks to the fetus

Oral GLP1 Breakthrough Part of the recent growth in GLP-1 sales come from pill versions of the drugs

Supplementation with a multivitamin, calcium, and vitamin D may also be necessary.50,51 While these are general guidelines, more targeted research is needed to refine them for GLP-1 users specifically