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It is a very important antioxidant, participates in detoxification of certain drugs, toxic environmental chemicals, protects against lipid peroxidation and electrophiles, has antiviral effects, is involved in the biosynthesis of DNA, proteins, and leukotrienes, cell proliferation, apoptosis, neurotransmission, and neuromodulation

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Mice lacking Hmgcr in -cells exhibited low insulin concentrations and hyperglycemia attributable to decreases in both -cell mass and insulin secretion

Huang L, Lu J, Cerqueira B, Liu Y, Jiang Z, Duong T

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