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The most

5,6 In a 12-week randomized trial, supplementation with 1,200 mg per day of berberine and 600 mg per day of cinnamon significantly reduced fasting blood glucose, HbA1c, and low-density lipoprotein (LDL) levels in patients with type 2 diabetes, without producing significant changes in body weight or BMI

Gastroparesis or bowel obstruction

Secretion of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes: systematic review and meta-analysis of clinical studies

in fact, what was discovered, was yet another insulinotropic peptide from the gut (adding to the about 9 insulinotropic peptides already known to exist)

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