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Differences in severity of heroin dependence by route of administration: the importance of length of heroin use

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To mitigate this issue, a SsrA degradation tag was integrated into the Npu SICLOPPS inteins, enabling the bacterial protease ClpXP to degrade the spliced inteins

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Moreover, sinus tachycardia (58), transient increases in the mean pulse rate, acute kidney injury due to dehydration, and hypersensitivity reactions at the injection site have been described