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Retatrutide is part of a growing group of weight-loss drugs called GLP-1-based medications

The statements and products have not been evaluated by the U.S

A new study presented at the 2025 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS) examined how the timing of a patients last dose of Ozempic prior to total knee arthroplasty (TKA) or total hip arthroplasty (THA) influences anesthesia-related complications such as delayed emergence, aspiration, aspiration pneumonitis and conversion to intubation

The muscle-loss data especially deserves more attention when counseling patients

This prevents overlapping receptor activation that could intensify side effects beyond what either drug would produce alone

If additional glycemic control is needed, the dose can be increased in 2.5-mg increments every 4 weeks to a maximum of 15 mg once weekly