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G-protein coupled Estrogen receptor activation protects the viability of hyperoxia-treated primary murine retinal microglia by reducing Er stress
Expert Review of Neurotherapeutics11 :627-637
Chronic inflammatory and erosive arthritis also can develop in gout, particularly with poorly controlled hyperuricemia
The reactive metabolites induce oxidative stress by generating reactive oxygen species (ROS), which cause lipid peroxidation, protein modification, and DNA damage
A 2023 study in Virus Research found significantly elevated EBV reactivation markers in long COVID patients compared to recovered controls, suggesting that COVID-19 may disrupt the immune surveillance that normally keeps these dormant viruses in check
According to estimates, up to 15% of the general population may be vitamin B12 deficient
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