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In bipolar depression studies (up to 8 weeks), the most commonly observed adverse reactions associated with the use of SEROQUEL (incidence of 5% or greater) and observed at a rate on SEROQUEL at least twice that of placebo were somnolence (57%), dry mouth (44%), dizziness (18%), constipation (10%), and lethargy (5%)

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Researchers should note this distinction when contextualising MT-2 research within the broader literature

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