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Topical peptides are useful for certain applications (GHK-Cu copper peptide has reasonable evidence for topical activity), but for the major therapeutic peptides growth hormone secretagogues, BPC-157, Epithalon systemic delivery is required to produce the effects seen in the research literature

It pairs well with hormone or nutrient testing to identify any underlying deficiencies before supplementation

The PLAG1-GDH1 axis promotes anoikis resistance and tumor metastasis through CamKK2-AMPK signaling in LKB1-deficient lung cancer

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This can be especially beneficial for acne scars, sun-damaged areas, or skin recovering from cosmetic treatments

While each peptide independently supports the bodys natural growth hormone (GH) production, their combined use leverages complementary mechanisms of action that may produce more robust and balanced results than either peptide alone