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After its made in the skin as vitamin D3 (cholecalciferol), it becomes converted by the liver and kidney into a secosteroid hormone (calcitriol) that has receptors in practically all our tissues

These symptoms are usually mild and may subside as the body adjusts

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More recent research suggests the story is more complicated

Healthy skin care routines : sun protection, good moisturization, antioxidants via diet, adequate sleep natural ways to improve skin health without risking invasive procedures

Second, the biological environment itself plays a role