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Beyond fertility: polycystic ovary syndrome and long-term health

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Centrally, it crosses the bloodbrain barrier to engage GLP-1 receptors in the arcuate nucleus and brainstem, modulating POMC neurons and other appetite-regulatory circuits to reduce food intake and cravings

ChaC1 serves as a reliable indicator for poor prognosis of certain types of gastric cancer (63) and melanoma (75,76), as well as an independent indicator for elevated risk for female germ line tumors (including breast and ovarian cancer) (77)

In recent years, understanding of the aetiology of the disease has improved with a number of studies investigating the molecular mechanism behind the loss of melanocytes in vitiligo [37]