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Ad-hoc "we'll see how it goes" is not adequate for a serious medicine

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Pharmacokinetic studies show that peptide medications like semaglutide degrade more rapidly when exposed to heat or light

The perception of higher bioavailability at 90-100% overlooks rapid clearance that eliminates therapeutic benefit

While urinary excretion of VC metabolites (oxalate, threonate) maintains systemic balance, prolonged deficiency ( ShacterEet alAscorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo

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