Monosodium urate (MSU) crystals deposited in synovial tissue can interact with the innate immune system, triggering an inflammatory response that results in typical symptoms of gout, including pain, swelling, and redness [7]
Ultimately, the understanding of systemic and brain PK of 7,8-DHF among neonatal mice could be applied to larger animal models of neonatal HIE especially the ones that show the kidney and liver injury phenotype that is not present in Vannuccis neonatal rodent model of HI
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Overexpression of Plakophilin2 mitigates capillary leak syndrome in severe acute pancreatitis by activating the p38/MAPK signaling pathway
The dorsal putamen was selected as the center of the volume of interest due to its relatively homogenous mix of neurons and astrocytes, and suitable distance from bone and other regions that could compromise signal quality