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Machine learning identifies large-scale reward-related activity modulated by dopaminergic enhancement in major depression

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GLP-1 receptor agonists can also be considered, though weight loss targets differ: guidelines recommend a 3% to 5% weight loss for lean patients instead of 10% or more for patients with obesity

Proteins of cardiomyopathic relevance were similarly mapped, and determined to include cardiac troponin I3 (TNI3), actin gamma 1 (ACTG1), actin alpha cardiac muscle 1 (ACTC1), tropomyosin (TPM), myosin light chain (MYL2-3), and myosin heavy chain (MYH6/7)