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Metformin significantly reduced the proportion of SW837 cells in G2/M phase at both 6 h and 10 h post irradiation with 1.8 Gy, when compared to irradiated vehicle control ( Figure 2H )

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The principle was proven yet again in 2008, when Bitonti and colleagues showed that also small FcRn-binding peptides could increase the catabolism of IgG in both mice and NHPs [117]

Its stability and resistance to degradation in the gastrointestinal tract make it a unique subject for both systemic and oral administration models

Blanco, R

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