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While some MRS data showed region-specific increases, the overall trend pointed to rising oxidative stress with age (13)

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However, Eggers test detected a significant risk of publication bias in MCI brain GSH literature (bias [95%CI] = 11.28 [20.6, 1.95], p =0.03) and AD blood GSH literature (bias [95%CI] = 5.18 [9.96, 0.40], p =0.035)

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