There are several incretins including GLP-1 and GIP
GLP-1 has been reported to improve glucose-dependent insulin action through the G-protein-coupled receptor, GLP-1R ( GLP-1 is involved in the regulation of energy balance (Holst, 2007), and its activation and subsequent binding to the GLP-1R reduces food intake and, consequently, body weight (Turton et al., 1996)
Energy levels typically improve by week three as the body adapts to its new fuel availability
Mechanism of action: Mounjaro works by mimicking the naturally occurring gut hormones GLP-1 and GIP (sometimes also called gastric inhibitory polypeptide)
Williams is starring in a national marketing campaign spanning digital, broadcast, and out-of-home that highlights her story and how Ro helps members like Williams achieve their health goals
Ro Body vs TrimRx: which GLP-1 program is better in 2026