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Progress in Neurobiology

Interspecies scaling (for example, body-surface-area conversion) typically reduces a rodent mg/kg figure severalfold, and even a properly scaled number would still be a hypothetical exposure , not a validated dose

Graphic abstract Access this article Similar content being viewed by others Notes Ion-pairing arising from relatively high ion concentrations varies with solvent, and thus can strongly influence acid strength in different solvents

Science 358, 13181323

It binds to toxins, making them water-soluble so they can be filtered out of the body