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Even with high concentrations of SnCE1 enzyme used and overnight incubation, we observe only partial cleavage of the Lys63-linked diUb chains (Fig

The role of autophagy in neurodegenerative disease

Moreover, ROS levels, pivotal markers of oxidative stress, surged post-GR knockout, across total, intracellular, and supernatant ROS ratios ( P = 0.0016, P = 0.0005, and P = 0.0247, respectively) (Figures 6GI), with intracellular elevations being particularly significant

doi: 10.2174/13816128113199990559 61

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