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None of them has undergone the kind of large-scale trials to establish safety and effectiveness that are required for FDA drug approvals

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Through the 1970s and 1980s, gastric-physiology research had established the concept of "cytoprotection" the observation by Andr Robert and others that certain agents could protect gastric mucosa against injury without reducing acid secretion [1]

doi: 10.1039/D1TC04147A 154 LiX-GLiJChenJRaoLZhengLYuFet al

Carnitine is concentrated in tissues that utilize fatty acids as fuel, like skeletal and cardiac muscles