When examining the relationship between baseline glutathione levels, the responders ( n = 12) had significantly higher baseline concentrations of both total and reduced glutathione than baseline and non-responders ( n = 8)
Specifically, we and other groups have reported that detached and metastasizing OVCA cells are especially vulnerable to ferroptosis 9,10,11,12 , a form of cell death characterized by iron dependency and an irreversible accumulation of lipid hydroperoxides 13
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The resulting quadratically constrained problem can be solved to optimality by mathematical solvers
Junyu Zhao, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
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