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The SELECT trial, published in the New England Journal of Medicine in 2023, demonstrated that semaglutide significantly reduced major adverse cardiovascular events in patients with established cardiovascular disease and overweight or obesity, representing a landmark finding for GLP-1 receptor agonists in cardiovascular risk reduction

Zhang H, Yang G, Chen H, Wei B, Ke Q, Guo H, et al

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Reddys Laboratories, and Lupin are already working on GLP-1-based therapies, preparing for increased demand once patents expire in 2026 in various global markets

A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans