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Sequencing was performed using a HiSeq 2500 (Illumina), with a read length of 300 bp paired-end reads and at least 25,000 tags per sample

The disulphide bond between the two cysteine residues creates a constrained loop structure that is believed to be important for the compounds specific receptor interactions in metabolic research models

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Studies investigating the relative selectivity of PT-141 vs MT-II across the melanocortin receptor family contribute to understanding which receptor subtype drives which observed effect

21,34,35 Atherosclerosis Progression Atherosclerosis develops over many years