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Elevated blood pressure, cardiometabolic risk and target organ damage in youth with overweight and obesity

The result may be greater oxidative stress and reduced neurological resilience

The accelerated healing in burns of treated mice includes the activity of the pentadecapeptide BPC 157 (Figure 1), given locally (as a cream) or systemically (ip), on the inflammatory cells, edema, reticulin, collagen, necrosis, blood vessel formation, number of preserved follicles, re-epithelization, tensile breaking strength, and water content in burned skin

Potential mechanisms by which peptide exposure could influence surgical outcomes include dysregulated angiogenesis contributing to hematoma formation, altered inflammatory signaling affecting early wound healing, and perturbations in collagen organization that may influence soft-tissue integrity during the critical postoperative period

Estos hallazgos posicionan al sistema NO como una de las vas centrales a travs de las cuales BPC-157 ejerce sus efectos citoprotectores observados en modelos preclnicos