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Catecholamine Cascade : Once L-DOPA is formed, it converts to dopamine through aromatic L-amino acid decarboxylase, then proceeds to neurotransmitter norepinephrine via dopamine beta-hydroxylase, and finally to epinephrine in adrenal tissues

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Beetroot extract may have an additive effect when combined with blood pressure-lowering drugs, including: ACE inhibitors (e.g., ramipril, lisinopril) Angiotensin receptor blockers (ARBs) (e.g., losartan, candesartan) Beta-blockers (e.g., bisoprolol, atenolol) Calcium channel blockers (e.g., amlodipine, diltiazem) Diuretics (e.g., bendroflumethiazide, furosemide) This combination may result in excessive hypotension, causing dizziness, syncope, or fallsparticularly concerning in elderly patients

Jung SW, Kim HJ, Lee BH, Choi SH, Kim HS, Choi YK, et al

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