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CJC-1295 raises the baseline amplitude of the GH pulse, while Ipamorelin increases the frequency and strength of the secretion

Side effects were consistent with those seen for obesity therapies, including gastrointestinal symptoms (nausea, diarrhea and constipation) and an elevated rate of dysesthesia (abnormal skin sensations), reported in about 20.9% of patients on the highest dose

This has generated interest in its potential future role in obesity management and metabolic health

The gut, in particular, contains the highest density of immune cells in the body and acts as a major inflammatory signaling hub

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