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Tubular epithelial fibroblast transdifferentiation (TEMT) has been proposed as a viable therapeutic option to decrease RF since it stimulates the expression of several fibro-cytokines, which represent a critical mechanism in the development of RF (Li et al., 2004

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Senescent cells in the scalp essentially poison the follicular environment, secreting pro-inflammatory signals that impair neighboring follicles

doi:10.3390/ijms19072029 227