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In cases where the deficiency is due to an underlying condition, treating the underlying cause may also be necessary

These studies established an excellent safety and tolerability profile, with no serious adverse events attributed to the compound

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Then, the rats started to drink excessively, then to eat and repeatedly drink water for a period of a few minutes after which they regained normal behavior, drank and then ate and showed no behavioral abnormalities until their sacrifice ( Table 6 )

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As no effective therapies to retard or reverse disc degeneration have yet been devised, there is huge interest in potential regenerative treatments for human patients