A DSM study from the human nutrition and health department (59) describes hydroxytyrosol as the most powerful anti-inflammatory compound among polyphenols of olive oil, showing effective inhibition in the production of NO and PGE2, decreasing secretion of cytokines (IL-1, IL-1, IL-6, IL-12, TNF-) and chemokines (CXCL10/IP-10, CCL2/MPC-1) and reducing gene expression of iNOS, IL-1, CXCL10/IP-10, MIP-1, matrix metaloproteinase-9, and prostaglandin E2 synthase (PGES)
Liver Function Matters The liver plays a central role in the GH-IGF-1 axis
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Stick to a whole-foods-based diet with plenty of fresh vegetables, lean proteins, and B12-rich foods like eggs and dairy
It is recommended for two distinct indications: It is indicated in the treatment of vitamin B12 deficiency due to a lack of absorption - biermer's disease, - ablation of the stomach or part of the intestine, - imerslund's disease, and in this case it should be administered by intramuscular injection
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