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The formulation was constructed by encapsulating GYY4137 within liposomes and coating the surface with Eudragit S100, a well-established pH-sensitive polymer that dissolves at pH 7 and is widely recognized for colon-targeted delivery due to its safety and biocompatibility [53]

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We observed that livers from Gclc L-KO mice had increased expression of NRF1 protein (Fig

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