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If a true plateau persists at maximum dose for 8+ weeks, your clinician may consider switching to tirzepatide or adding an adjunct such as naltrexone-bupropion

Even when it means tossing a bit of unused medicine, its worth it to protect your health and ensure every dose is working as intended

No data exists beyond four years, but the safety profile suggests longer use is likely safe for most people

Hyperpigmentation following inflammation may be caused by an increase in melanogenesis triggered by cytokines and reactive oxygen species, which induce melanocyte activity and the proliferation of dendritic cells, and increase tyrosinase activity [31, 32]

you'll see online bitching about disorganization from ex-employees

Theyre supportive tools, not a replacement for treatment