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Retatrutide is an investigational injectable peptide medicine currently under clinical development by Eli Lilly and Company

Risks appear particularly elevated in individuals with comorbid depression or BED, where long-term outcomesespecially following discontinuation of pharmacotherapyremain insufficiently studied [143]

(Source: Healthline, 2026) The BALANCE Model Has Been Delayed Indefinitely CMS originally announced two programs: the GLP-1 Bridge Program and the BALANCE model (Better Approaches to Lifestyle and Nutrition for Comprehensive Health), a five-year CMS Innovation Center model that would have let Part D plans opt in to covering weight loss GLP-1s starting January 2027

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