in the latter, proopiomelanocortin (POMC) neurons are present and it is believed that endogenous GLP-1 induces satiety, affecting both anorexigenic and orexigenic signaling pathways
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In some cases, temporary dose reduction or pausing dose escalation of the GLP-1 medication may be appropriate while nutritional status is optimized, though this decision should be made collaboratively between patient and provider
Mixed: Mood and Mental Health Because GLP-1 receptors influence mood and factors like blood sugar, appetite, and sleep, and because rapid body changes also play a role, experiences vary widely
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Understanding how GLP-1 medications work, what realistic outcomes to expect, and who may be suitable for treatment is essential for informed decision-making