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Composition, proportion and diversity of an individuals gut microbiota are affected by genetics, lifestyle (diet), drugs (frequency/use of antibiotics), aging and other factors

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This medication neutralizing harmful free radicals, aiding liver detox processes, and supporting cellular repair

Mitochondria also regulate calcium homeostasis, reactive oxygen species (ROS) production, intracellular communication and apoptosis

Imaging cytosolic NADH-NAD(+) redox state with a genetically encoded fluorescent biosensor

A parallel line of work frames Alzheimers disease as a state of central insulin resistance, sometimes called type 3 diabetes, in which GLP-1R agonism restores neuronal insulin signalling, improves mitochondrial function, and reduces oxidative stress