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Since the polymer systems of thermoreversible gels dissolve more completely at reduced temperatures, methods of solubilization include adding the required amount of polymer to the amount of water to be used at reduced temperatures

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Also, a mouse model for late-onset mitochondrial myopathy due to overexpression of mutated Twinkle protein, a nuclear-encoded replicative helicase of mtDNA, showed clear health improvements after 10 months of KD

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