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To test the effect of sustained repression of lipogenic programs and a concurrent sustained induction of NRF2 activity, we monitored mice for ten weeks following the induction of Gclc deletion alone (Gclc L-KO) or in combination with Nrf2 deletion (L-DKO) in the liver (Fig

Researchers discovered that miRNAs are linked to the hub genes in the miRNAhub gene network and regulate the hub gene expression during POP (Zhou et al

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doi: 10.1007/s10654-021-00754-4

Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors