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In patients in whom the major therapeutic goal is the compelling need to minimize the therapeutic risk pf hypoglycaemia, DPP-4 inhibitors are recommended as second line therapy after metformin failure at the same level as second line treatment options with GLP-1 receptor agonists, SGLT-2 inhibitors, or TZDs
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Endocrinology 151: 1984-1989, 2010
Verma S, McMurray JJV
Research shows increased lifespan in animal models, delayed onset of age-related diseases, and improved immune competence with combined use
Eli Lilly TRIUMPH-1 Phase 3 obesity announcement
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