& Butterfield, L
2,3 Approximately 2% of people in the United States have fibromyalgia, although the prevalence varies across populations and with the diagnostic criteria used
GSS AA Sequence ATNWGSLLQDKQQLEELARQAVDRALAEGVLLRTSQEPTSSEVVSYAPFTLFPSLVPSALLEQAYAVQMDFNLLVDAVSQNAAFLEQTLSSTIKQDDFTARLFDIHKQVLKEGIAQTVFLGLNRSDYMFQRSADGSPALKQIEINTISASFGGLASRTPAVHRHVLSVLSKTKEAGKILSNNPSKGLALGIAKAWELYGSPNALVLLIAQEKERNIFDQRAIENELLARNIHVIRRTFEDISEKGSLDQDRRLFVDGQEIAVVYFRDGYMPRQYSLQNWEARLLLERSHAAKCPDIATQLAGTKKVQQELSRPGMLEMLLPGQPEAVARLRATFAGLYSLDVGEEGDQAIAEALAAPSRFVLKPQREGGGNNLYGEEMVQALKQLKDSEERASYILMEKIEPEPFENCLLRPGSPARVVQCISELGIFGVYVRQEKTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPV Predicted Molecular Mass 53.5 kDa Molecular Weight Approximately 55 kDa, based on SDS-PAGE under reducing conditions
Release 350 , 8092 (2022)
Abbreviations AOAA aminooxyacetic acid AVG L-aminoethoxyvinylglycine BCA -cyano-L-alanine CARS cysteinyl-tRNA synthetase CBS cystathionine -synthase CSE cystathionine -lyase HMPSNE 2-[(4-hydroxy-6-methylpyrimidin-2-yl)sulfanyl]-1-(naphthalen-1-yl)ethan-1-one MST 3-mercaptopyruvate sulfurtransferase NAC N-acetylocysteine PAG DL-propargyl-glycine PLP pyridoxal phosphate RSS reactive sulfur species Competing Interests These authors declare that there are no competing interests associated with the manuscript
In some cases, patients may also experience more severe side effects, including respiratory depression or altered mental status, particularly if they are on other medications that also affect the central nervous system