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B12 shots are injected intramuscularly, which means they dont have to go through the digestive system like an oral supplement

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However, such transitions are complex and will take years to implement

Ethics declarations Ethics approval and consent to participate All animal experiments in this study were carried out in conformity with the Guidelines for the Use and Care of Laboratory Animals of the National Institutes of Health and were approved by the Institutional Animal Care and Use Committee (IACUC) of Nanjing Medical University (IACUC-2306028)