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Glutathione-S-Transferases Structure, Function and Clinical Implications

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Of more than 100 compounds synthesized and tested for TGR inhibition (a more thorough description of compound design will form the basis of a future manuscript), the most promising were selected to be extensively characterized in the in vitro and in vivo studies described below

However, it remains under investigation whether these benefits are directly due to the GLP-1 agonists or a result of the weight loss they facilitate