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doi: 10.1001/archinte.160.4.526 72 HollowellJGStaehlingNWFlandersWDHannonWHGunterEWSpencerCAet al

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This also pinpointed when glutathione is specifically required: during the early steps of metastatic colonization, when cancer cells adapt rapidly to the stressful environment of a new tissue

Although total GR activity was increased, no improvement in cold tolerance occurred

doi: 10.1002/iub.2339 53 FoellDWittkowskiHRothJ

Notably, in the condition of excess hemin exposure and hypoxia, our findings suggest an important contribution of the TSS pathway and its regulation by DMF for de novo cysteine synthesis and GSH generation in protecting against the oxidative and ferroptotic stresses in SCD erythroblasts