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Genetics 187 , 485499 (2011)

Acetylcholine via the vagus nerve can also stimulate some stomach acid release by stimulating M3 (muscarinic acetylcholine) receptors

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12, 13, 14 Together, the pathological features of T2Dnotably elevated serum concentrations of inflammatory cytokines, glucose, insulin and free insulin-like growth factor-1 (IGF-1)provide a pro-tumorigenic environment that may account for the increased risk of diabetic and obese patients for the development of cancer at various sites 11 as well as the worse prognosis of patients with cancer that display one or more of these abnormalities