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Its triple-hormone mechanism is studied for how it may suppress appetite, support glucose-dependent insulin secretion, and increase energy expenditure

Beclin-1, a key protein in autophagy initiation, was reduced by 60% in DOX muscle compared to control, indicating impaired autophagic signaling

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One notable exception is oral semaglutide (Rybelsus) for diabetes treatment, which uses special absorption enhancement technology

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