cons of retatrutide Retatrutide, an experimental weight-loss drug, has not been approved by the FDA. But, doctors and nurse practitioners in clinics across the country are prescribing it anyway, a CBS News investigation Retatrutide and the Grey Market:

However, here is why you might want to skip the psyllium husk if you are on a weight-loss medication: Delayed Gastric Emptying: Medications like Ozempic, Wegovy, Mounjaro, Zepbound and Retatrutide intentionally slow down your digestive tract

Its unclear if the adverse effect will impact retatrutides prospects

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Reddit, August 20, 2025 The incident is a stark reminder that people taking versions of the as-yet unapproved weight loss medicine may not receive safe products and have no authority to turn to if anything unexpected happens

Based on clinical trial data, retatrutide produces greater average weight loss (28.7% at 68 weeks with 12mg) compared to tirzepatide (22.5% at 72 weeks with 15mg)