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The following data were extracted from the interventional studies: authors names and year of publication, study design and washout time, dosage, substance and intervention duration, number, sex and age of participants, sport level and cognitive aspects which were assessed

Lack of clinical evidence and human trial data While the mechanisms of action of Schisandra chinensis and its lignans are well-documented, the majority of research is preclinical, with only a few human studies available [121,122,123,124]

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Tirzepatide is an FDA- and EMA-approved dual GIP/GLP-1 receptor agonist with multiple completed Phase 3 trials behind it