retatrutide phase 2 trial ESC 2024: improves lipid and cardiovascular risk profile in II LLY's Retatrutide Nears 2027 Filing

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doi:10.1242/jcs.034355

doi: 10.1016/j.jbiosc.2023.12.004 25 EffendiR

In contrast, evidence points to simple, actionable behaviors that can significantly reduce obesity risk

(1) Omega-3 PUFAs (EPA/DHA) as core antidepressant components Deep-sea fish (e.g., salmon, mackerel) contain 23 g/100 g of EPA and DHA, which target two key pathways of depression: Inhibiting microglial activation: by inhibiting the NF-B/MAPK p38 signaling pathway and activating the neuronal BDNF-PI3K/AKT pathway, the process achieves a balance in microglial M1/M2 polarization and provides neuroprotection against neuroinflammation (313)

Ulcerative colitis is a type of IBD that affects the colon