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The compound appears at measurable concentrations in human plasma, saliva, and urine, and its levels are known to decline with age a pattern that has driven considerable interest in its study as a research tool
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Botulinum neurotoxin type A (BoNT/A), an exotoxin from Clostridium botulinum, reversed the downregulation of type II collagen and the upregulation of MMP-13 induced by LPS in chondrocytes, alleviating LPS-induced chondrocyte toxicity, activating the SLC7A11/GPX4 antiferroptotic system, and enhancing mitochondrial function
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