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Andrew: Then we'll get around to the fact that BPC has, let's hope temporarily, been taken off market and what some of the alternatives are

The PIONEER trial programme used two estimands to address two different efficacy questions [39]

"Essentially every insurance carrier is just making it up, making up the policy, the limitation, the restriction on eligibility in the way that they want to, in a way that will kind of reduce the eligible population," Zvenyach says

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Concerned about costs

The primary outcome was resolution of MASH without worsening of fibrosis at 52 weeks as determined by liver biopsy (Fig