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The FDA recommends Wegovy for weight loss if you meet one of the following criteria: Have a body mass index (BMI) of 27kg/m2 or greater and at least one weight-related condition, such as high blood pressure, Type 2 diabetes or high cholesterol Have a BMI of 30kg/m2 or greater Avoid semaglutide if you have: History of medullary thyroid cancer History of gallbladder disease History of pancreatitis Multiple endocrine neoplasia syndrome type 2 (MEN2) If youre considering semaglutide for weight loss, your first step should be consulting your primary care physician (PCP)

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Wald DS, et al

Major mediators linking inflammation and cancer, in Cancer and Chemoprevention: An Overview

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Furthermore, many studies indicate a down-regulation of IGF-1R upon cancer progression, whereas others report elevated levels in metastatic stages