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For example, the transsynaptic complexes of dystroglycans and neurexins correlate with the function of synaptic transmission [60], neurexins-LRRTMs transsynaptic complexes regulate presynaptic differentiation [61], neurexins-calsyntenins transsynaptic complexes correlate with inhibitory synapse formation and function [62] and neurexins-latrophilins transsynaptic complexes are associated with synaptic excitatory mechanisms Ca 2+ independent release [63]

The presence of these contaminants can severely compromise research and introduce unknown toxicity

The result is a self-perpetuating cycle of barrier damage, immune activation, and recurring symptoms

A., Bunzow J

doi:10.1016/j.urology.2020.07.087

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